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Evaluating the impact of entrepreneurship education is difficult given the heterogeneity of programming which presents challenges related to the generalizability of findings. The National Science Foundation’s Innovation-Corps (I-Corps) program, which incentivizes academic researchers to explore the commercialization potential of their research, offers a unique opportunity to examine the outcomes of entrepreneurship and technology commercialization training from an educational perspective given its standardization across populations and settings. We used the four-level Kirkpatrick Model for evaluating the impact of training and education programs to examine faculty experiences with I-Corps in depth. Using a qualitative inquiry methodology, we conducted 26 interviews with faculty innovators across three large public research institutions. Findings revealed that faculty had positive impressions of the program overall and attributed specific knowledge gains to participation. They also described behavioral changes impacting both their research and teaching. However, participants also identified challenges with I-Corps pedagogy and identified opportunities to improve training. This program evaluation and description of specific learning outcomes (skills, knowledge, attitude, and behaviors) contributes to best practices associated with delivering technology commercialization and entrepreneurship training to academic researchers.